Ecological fitness, genomic islands and bacterial pathogenicity
نویسندگان
چکیده
منابع مشابه
Ecological fitness, genomic islands and bacterial pathogenicity
The compositions of bacterial genomes can be changed rapidly and dramatically through a variety of processes including horizontal gene transfer. This form of change is key to bacterial evolution, as it leads to ‘evolution in quantum leaps’. Horizontal gene transfer entails the incorporation of genetic elements transferred from another organism—perhaps in an earlier generation—directly into the ...
متن کاملPathogenicity islands in bacterial pathogenesis.
In this review, we focus on a group of mobile genetic elements designated pathogenicity islands (PAI). These elements play a pivotal role in the virulence of bacterial pathogens of humans and are also essential for virulence in pathogens of animals and plants. Characteristic molecular features of PAI of important human pathogens and their role in pathogenesis are described. The availability of ...
متن کاملPathogenicity Islands: Bacterial Evolution in Quantum Leaps
(Van Gijsegem et al., 1993)—and these systems differ from the sec-dependent pathway in that their effector moleSt. Louis, Missouri 63110 † Department of Biology cules lack a typical signal sequence. At the same location where LEE has inserted into entero-pathogenic strains (McDaniel et al., 1995) a distinct patho-genicity island, PAI-1, has been identified in a uropatho-" I am the beneficiary o...
متن کاملThe Role of Genomic Islands , Mutation , and Displacement in the Origin of Bacterial Pathogenicity
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متن کاملPathogenicity islands: a molecular toolbox for bacterial virulence.
Pathogenicity islands (PAIs) are distinct genetic elements on the chromosomes of a large number of bacterial pathogens. PAIs encode various virulence factors and are normally absent from non-pathogenic strains of the same or closely related species. PAIs are considered to be a subclass of genomic islands that are acquired by horizontal gene transfer via transduction, conjugation and transformat...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2001
ISSN: 1469-221X,1469-3178
DOI: 10.1093/embo-reports/kve097